设定于英国古城约克，人物也清一色更为英文名：　　拥有自闭症的档案管理员PatienceEvans由EllaMaisyPurvis饰演；发现Patience奇才的探长BeaMetcalf由LauraFraser饰演。　　本剧中所有神经多样性角色都由神经多样性演员出演，包括主角Patience。

Returningforanextendeddurationofeightepisodes,Patience(EllaMaisyPurvis)willcontinueherworkinthepolicecriminalrecordsdepartmentofCityofYorkPoliceafterestablishingherselfasaninvaluablememberoftheteam,bringingheruniqueinsightintoaseriesofperplexingcases.However,whenanewboss,DetectiveFrankieMonroe(JessicaHynes)bringsaverydifferentmanagementstyle,itprovestrickyforthembothtonavigate.LoveisalsointheairinthisseriesasPatiencebeginsarelationshipwithaworkcolleagueElliotandthepolicedepartmentgetsamakeoverwiththearrivalofanewPRconsultantallwhilsttacklingintriguingcrimesinextraordinarysettingssuchasYorkMinster.